Proteins fulfill complex and diverse biological functions through the controlled atomic motions of their structures (functional dynamics).The protein composition is given by its amino-acid sequence, which was assumed to encode the function.However, the discovery of functional sequence variants proved that the functional encoding does not come down
Ecological investigations of the terrestrial vegetation were made as a part of the studies on the ecosystem to serve as the background for an evaluation of the effects of environmental contamination by human activities in the Antarctic.Under the project of the 16th Japanese Antarctic Research Expedition (JARE-16), field investigations were carried
Abstract Background Somatic alterations, including loss of heterozygosity, can affect the expression of oncogenes and tumor suppressor genes.Whole genome sequencing enables detailed characterization of such aberrations.However, due to the limitations of current high throughput sequencing technologies, this task remains challenging.Hence, accurate a
Abstract Background The majority of surgical wounds are closed (for example with sutures or staples) and so heal by primary intention.Where closure is not possible, or the wound subsequently breaks down, wounds may be left to heal from the bottom up (healing by secondary intention).Surgical wound healing by secondary intention (SWHSI) frequently pr
BackgroundChina is experiencing rapid population aging, with the proportion of older adult people aged 60 and above reaching 19.8% of the total population in 2022.With the Mulberry Leaf growth of age, the physical function of older adults declines and their mental health is getting worse, with the increasing trend of empty nesting and childlessness